2013
5/20 Michael Levin, Professor, Tufts University Endogenous voltage gradients and cancer as a development disorder: patterning cues in the microenvironment that control carcinogenesis PS-OC/IMO Seminar
5/17 Trevor Graham, Center for Evolution and Cancer Measuring clonal evolution in cancer: patterns, pace and prognostic value PS-OC/IMO Seminar
3/21 Sui Huang, Professor, Institute for Systems Biology Cancer attractors and cancer cell population dynamics: A framework for non-genetic, non-darwinian evolution of cancer drug resistance PS-OC/IMO Seminar
2/21 Philip Maini, Professor, Centre for Mathematical Biology, Mathematical Institute Modeling invasive process in biology PS-OC/IMO Seminar
1/31 Amina A. Qutub, Assistant Professor, Rice University Endotheilial cells as state machines: predicting and controlling capillary development PS-OC/IMO Seminar
Previous IMO Weekly Seminars
2012
11/30 Arne Traulsen, Professor, Max-Planck Institute for Evolutionary Biology The dynamics of mutant clones in hierachically organized tissues and their potential PS-OC/IMO Seminar
9/6 Jason Hammond, IMO Post Doc Candidate, Statisical Cancer
8/17 Hemachander Subramanian, Post Doc Candidate (Gatenby), Interaction of magnetism with geometry
8/16 Wenfeng Kang, IMO Post Doc Candidate, Statistical Methodologies to optimize clinical trial design for cominatorial therapies against cancer
7/19 Deborah C. Markha, University of Oxford, Modelling somatic evolution in ductal carcnomas PS-OC -IMO Seminar
7/10 Paul Orlando, Research Fellow, NIH, Cancer treatment as a game
6/29 Thomas Hillen, M.D., Professor, Graduate Chair, Department of Mathematical and Statiscal Sciences/University of Alberta, Modelling of cell movement in tissues and application to glioma growth
6/14 Uwe Rix, Ph.D., Assistant Member, Drug Discovery/Moffitt, Systems pharmacology approaches for the dissection and prediction ofdrug action
5/21 James A. Glazier, Professor, DBiocomplexity Institute and Department of Physics, Indiana University, Applying multi-scale, multi cell modeling of pathological neovascularization in the retina and solid tumors to suggest novel treatment strategies PS-OC/IMO Seminar
5/16 Muhammad H. Zaman, Ph.D. Assistant Professor, Department of Biomedical Engineering and Medicine, Boston University, Quantiative systems level understanding of tumor cell-matrix interactions in 3 D environments PS-OC/IMO Seminar
4/27 Mark Lloyd, Core Staff Scientist, Analytic Microscopy/Moffitt, Image (in)e the possibilities
3/8 Prakash Chinnayan, Ph.D., Assistant Member, Radiation Oncology/Moffitt. TBA
2/23 Elena Fertig, John Hopkins University, Modelling complex biochemical systems: lessons from numberical weather prediction PS-OC/IMO Seminar
2/2 Philip Gerlee, Ph.D. Post Doc, Cancer Center Sahlgrenska and Mathematical Sciences, Gothenburg University and Chalmers The impact of phenotypic switching on glioblastoma growth and invasion
1/30 Joao Xavier, Ph.D. Assistant Faculty Member, Computational Biology, Memorial Sloan Cancer Center Robustness in multicellularity PS-OC/IMO Seminar
2011
11/21 Katie Bentley, Ph.D., Vascular Biology Lab, CancerResearch UK, Time to branch? Simulations uncover newtemporal and spatial dynamics of tip cells in angiogenesis
11/18 Miguel Herrero, Ph.D. Professor, Department of Applied MathematicsUniversity of Complutense de Madrid OptimizationProblems in Radiotherapy Dosimetry Planning
10/13 Ziv Frankenstein Ph.D., Weizmann Institute of Science(IMO Post Doc Candidate) Thecytokine network architecture of intercellular communication
9/8 Melvyn S. Tockman, MD, Ph.D. Moffitt, Senior Member, Research Looking at the Tumor's Edge
6/23 Irakli Loladze, Ph.D., Arizona State University (IMOPost Doc Candidate) Growth Rate and Stoichiometric Homeostasis in Cells andEcosystems: An Evolutionary Model based on Biomolecular Synthesis
6/22 Michael W. Conroy, Ph.D., University of South Florida(IMO Post Doc Candidate) Modelsof Liquid Loss and Non-Newtonian Flow for Firefighting High-Expansion AqueousFoams
6/20 Jayant Avva, Ph.D., Case Western Reserve University,(IMO Post Doc Candidate) AMethodology for Dynamic Expression Profile Extraction from Cytometry Data
6/16 Mun Ju Kim,Ph.D., University of Pittsburgh (IMOPost Doc Candidate) Computational Models of T-Cell Killing Apparatus Aim Adjustment
5/16 Marcus Owen, Ph.D., The University of Nottingham Mathematical Modeling Predicts SynergisticBenefits of Combining a Macrophage-Based Therapy with Chemotherapy
5/12 Steven A. Eschrich, Ph.D., Moffitt Genes, Proteins and Networks: MolecularAnalysis in Translational Research
5/5 David Axelrod, Ph.D., Rutgers University Stem Cell Dynamics in Normal Human ColonCrypts and the Progression to Colon Cancer PS-OC/IMO Seminar
4/22 Timothy W. Secomb, Ph.D., University ofArizona Growth and Structural Adaptation ofMicrocirculation in Normal and Tumor Tissues PS-OC/IMO Seminar
4/7 Leonid A. Mirny, Ph.D., M.I.T. On Drivers and Passengers: A New EvolutionaryModel of Cancer Progression PS-OC/IMOSeminar
3/24 Steve S. Brem, M.D., Moffitt Developing Treatments of Malignant GliomasUsing Inhibitors of Angiogenesis and Invasion: Potential Rose for IntegratedMathematical Modeling
3/7 Heiko Enderling, Ph.D. Tufts University Schoolof Medicine Modeling the Cancer Stem Cell Hypothesis and Implications for Treatment IMO-PSOC Seminar
2/24 Alvaro Monteiro, Ph.D., Moffitt Probing the DNA Damage Response Using Networks
2/14 Eric A Mellon, Ph.D., University ofPennsylvania In Vivo NMR Spectroscopy of dfficult to detect metabolites
2/3 Conor Lynch,Ph.D., Moffitt Mechanisms of Cell-Cell Interaction in the Metastatic Prostate-TumorBone Microenvironment
1/27 Paul Orlando, The University of Illinois at Chicago Evolutionary Ecology of HPV: Tradeoffs, Co-Existence, and Species Originsof High-Risked and Low-Risk Types IMO-PSOC Seminar
2010
12/9 Srikumar Chellappan, Ph.D., Moffitt, Novels Insightsinto Lung Cancer Stem-Like Cells, Angiogenesis and Metastasis
11/18 Prakash Chinnaiyan, M.D.,Moffitt, Targeting the Unfolded Protein Response (UPR) in Cancer: A CommonDenominator of Unregulated Cellular Growth
10/25 Timothy Newman, Ph.D.,;Arizona State University, Cancer Is Complex - But Is It Simple? IMO-PSOC Seminar
10/14 Michael Tomblyn, M.D., MS,;Moffitt, Dosimetric Challenges for Delivery ofIntrathecal Radioim
10/7 Jill Gallaher,Ph.D., IMO Post Doc Candidate, Pore Kinetics of Pure Lipid Bilayer Membranes at theMelting Transition
9/23 Shengyu Yang, Ph.D., Moffitt, CriticalRoles of Actin Cytoskeleton in Cancer Metastasis
9/20 Hongfei Wu,Ph.D., IMO Post Doc Candidate, Stability of Viscoelastic Drop to FinitePerturbation/Multi-scale Simulation of Droplets on Solid Surfaces
9/17 Hugo Aerts,Ph.D.,University of Maastricht, Identification of the Radioresistant Areas Within theTumor: Towards Dose Painting by Volumes
9/16 Amlan Chakraborty,Ph.D.,IMO Post Doc Candidate, Effects of Bidirectional Ocillatory Shear Stress on EndothelialCell Proliferation, Morphology and Atherogenic Gene Expressions
8/26 Haley Jane Abel,Ph.D.,Universityof Utah, Estimating Linkage Disequilibrium byGraphical Modeling
6/24 Fang Yin, Ph.D.,IMO Postdoc Candidate, Polymer Loop Brush Simulation Study Using Monte-Carlo andMolecular Dynamics
6/15 Kieran Smallbone, D.Phil,Manchester Centre forIntegrative Systems Biology, Cancelled
6/10 Trachette Jackson, Ph.D.,University of Michigan, Endothelial Cell-Targeted Anti-CancerTherapies IMO-PSOCSeminar
6/3 Volkan Sevim, Ph.D.,IMO Post Doc Candidate, Modeling Cyclic Dynamics in Gene Regulatory Networks:Transcriptional Cell-Cycle Oscillator in Yeast
5/27 Keiran Smalley, Ph.D., Moffitt, BRAF Inhibition in Melanoma: From Response toResistance
5/20 Eunjung Kim, Ph.D., IMO Post Doc Candidate, Mathematical Models for Matrix Mechanics and Cell-MatrixInteractions in Biological Systems
5/13 Eduardo Sotomayor, M.D., Moffitt, Targeting Histone Deacetylase 6 and 11 toRegulate Inflammation and Immune Tolerance
4/29 Craig Stevens, MD, Ph.D./Geoffrey Zhang, Ph.D., Moffitt, Deformable Image Registration and PulmonaryVentilation Calculation Using 4D CT
4/22 Eric Haura, M.D., Moffitt, Expanding Drug And Biomarker Space Through Protein-ProteinInteraction And Phosphoproteomic Networks
4/1 Virendra Kumar, Ph.D., Moffitt, Radiomics of Lung Cancer
4/1 Heather Cornnell, Ph.D., Moffitt, Measurement And Manipulation Of TheHeterogeneity Of The Physical Tumor Microenvironment
4/1 Narges Kharazani Tafreshi, Ph.D., Moffitt, Indentification Of Novel Cell-Surface TargetsSpecific to Breast Cancer for the Non-invasive Detection of Metastatic BreastCancer in Lymph Node
4/1 Jonathan Wojtkowski, Ph.D., Moffitt, Chronic Autophagy is a Cellular Adaptation toTumor Acidic pH Microenvironment
3/11 Timothy J. Yeatman, M.D., Moffitt, Molecular Signatures Of Cancer
2/25 Channa de Silva, Ph.D., Department of Chemistry& Biochemistry and Bio5 Institute, University of Arizona, Images of Cleavage: Tumor Proteases In Action
2/04 Mark Robertson-Tessi, IMO Post Doc Candidate, A Mathematical Model of Tumor-ImmuneInteractions
1/21 Bakhti Vasiev, Ph.D., University of Liverpool,UK, Pattern Formation in Excitable Systems with Applications toDevelopmental Biology
2009
12/17 JonathanWojtkowiak, Moffitt, Low pH induced phenotypes
12/10 Philip Maini, Centre for Mathematical Biology, University of Oxford, Some mathematical models of Cancer growth
11/19 Philip Gerlee, Niels Bohr Institute, Denmark, Evolving homeostatic tissue using geneticalgorithms
11/16 Peter Hinow, University of WisconsinMilwaukee, Spatial Model of Tumor-Host Interaction: Application ofChemotherapy
11/12 Ingeborg van Leeuwen, Karolinska Insitute,Sweden, From mathematical modelling to cell biology: (1) A multiscalemodel for intestinal tissue renewal; and (2) The p53 pathway: complexity,oscillations, and therapeutic exploitation
11/11 Carlo Maley, The Wistar Institute, TBA
10/20 Kristin Swanson, University of Washington, Personalized Mathematical Oncology:Patient-Specific Mathematical Modeling of Glioma Growth and Progression
10/15 Juan Del Valle, Moffitt, Targeting Oncoproteins with Natural Productand Secondary Structure Mimetics
10/01 Robert Gatenby, Moffitt, New ideas for discussion: 1. Evolutionarily enlightened therapy 2.An ensemble model of intracellular pathways
9/17 JamesDeGregori, University of Colorado, Denver, Adaptive Oncogenesis: relating stem cellfittness, aging and cancer
9/10 DmitryGabrilovich, Moffitt, Regulation of immune responses in cancer by myeloid-derivedsuppressor cells
9/03 SaidSebti, Moffitt, Drug discovery at Moffitt: from chemicalbiology to hypothesis-driven clinical trials
8/27 MarcoScianna, Department of Mathematics, Politecnico di Torino, Italy, Individual Cell Based Models for Cell Scatterof ARO and MLP-29 Cells in Response to Hepatocyte Growth
8/27 ChiaraGiverso, Department of Mathematics, Politecnico di Torino, Italy, Cellular Potts Model for Ovarian CancerMetastasis
7/09 Scott Antonia, Moffitt, Immunotherapy Translational Research At Moffitt
7/10 Edward Flach, Dresden Technical University, Germany Motility and the cellular Potts model. Muscledevelopment: slow twitch cell migration
6/04 Amanda Shanks, Yoonseok Kam, Ariosto Silva, Moffitt, IMO poster presentations
5/28 James Helm, Moffitt, Signaling Pathways and Outcomes in Pancreatic Cancer
5/21 Esteban Celis, Moffitt, Development of Optimized Epitope vaccines for Cancer
5/14 John Curd, Threshold Pharmaceuticals, Tumor hypoxia as a selective target for novel treatments incancer-lessons from the development of TH-302
5/07 S. Sendhil Velan, West Virginia University, Department of Radiology, Localized Multi-DimensionalMRS: Unraveling thehidden resonances at clinical field strengths
4/30 Liping Xu, Kavindra Nath, David Basanta, Moffitt, IMO poster presentations
4/23 Gerold Bepler, Moffitt, RRM1 in lung cancer
4/24 Gibin Powathil, University of Waterloo, Canada, Modeling brain tumor: effects ofmicroenvironment and associated therapeutic strategies
4/24 Cory Howk, Iowa State University, A mathematical model for IL6-induced differentiation of neuralprogenitor cells on a micropatterned polymer substrate
4/16 Jonathan Wojtkowiak, Moffitt, Autophagy: A matter of life and death
4/09 Gary V. Martinez, Arig Ibrahim Hashim, PrasantaDutta, Moffitt, IMO poster presentations
4/02 P. K. Burnette, Moffitt, T cell homeostatsis in Bone Marrow Failure Syndromes
3/19 Virendra Kumar, Moffitt, Magnetic resonance spectroscopy and imaging in prostate cancer
3/12 Peter Thelwall, Newcastle University, UK, Imaging oxidative stress defences with MRI
3/05 Amanda Baker, University of Arizona, Thioredoxin-interacting protein as a potential target forpancreatic cancer therapy
2/26 Ed Seto, Moffitt, The Biology of Histone Deacetylases
2/19 Anna Giuliano, Moffitt, The Natural History of Human Papillomavirus Infection in Men
2/18 Emi Shudo, Los Alamos National Laboratory, Hepatatis C virus kinetics during treatmentwith pegylated interferon alfa-2b. A model that allows for time-varying drugeffectiveness. & Dynamic optimization of the immune reaction againstvirus/bacteria infection
2/12 Dr. Yoonseok Kam, Moffitt, In vitro cancer migration-invasion assay design driven bymathematical models
2/05 Thomas Sellers, Moffitt, Approaches to determine ovarian cancer susceptibility
1/29 Samuel E. Day, University of Cambridge & NIH, DNP hyperpolarized 13C-MRI: an approach tostudy enzyme function using magnetic resonance spectroscopy and imaging
1/22 Eric Haura, Moffitt, Using shotgun phosphoproteomics to discern tyrosine kinasesignaling in cancer
1/21 Hugo Aerts, University of Maastricht, Computer assisted theragnostics: an individualized decisionsupport system
1/09 Natasha Kaleta Martin, University of Oxford, Biocarbonate therapy: from mice to humans withmathematical models
1/08 John Koomen, Moffitt, Cancer proteome cataloging and quantitative network analysis
12/18 William Dalton, Moffitt, Novel targets to inhibit and reversedrug resistance in hematologic malignances
12/11 Javier Torres-Roca, Moffitt, System biology modeling of theradiosensitivity network
12/04 Ami Radunskaya, Pomona College, Mathematical models of tumor-immune interactions
11/20 David Morse, Moffitt, Choline as a biomarker for breast cancer diagnosis and therapeuticresponse
11/13 Simon Hayward, Vanderbilt University, Cellular interactions andprostatecancer progression
11/06 Keiran Smalley, Moffitt, Using 3D cell culture models to bring newinsightsto cancer biology
10/30 Kasia Rejniak, Moffitt, IBCell model in cancer development andtreatment
10/23 Gerard Ostheimer, MIT, Data driven modeling of cellular senescenceandapoptosis after DNA damage
10/16 Lori Hazlehurst, Moffitt, The bone marrow microenvironmentcontributestowards resistance to BCR-ABL inhibitors in CML
10/09 Philip Tofilon, Moffitt, The microenvironment and glioblastomaradiosensitivity
9/25 Alexander Anderson, Moffitt, Microenvironment driven invasion: a multiscalemultimodel investigation
9/18 Robert Gilles, Moffitt, Acid-mediatedinvasion and bicarb treatment
9/11 David Basanta, Moffitt, Evolutionary game theory approaches to cancer modeling
9/04 Ariosto Silva, Moffitt, Adaptive therapy : an alternative cancer treatment