Cecile A. Lengacher, RN, PhD

Dr. Lengacher’s research includes women’s health, psycho-oncology, psychoneuroimmunology, and complementary alternative medicine. This expertise spans basic science to clinical research. An important aspect of her psycho-oncology research is symptom management through delivery of complementary alternative medicine  therapies.  She is currently conducting an NCI-funded study examining the effects of mindfulness-based stress reduction on symptom management and biomarkers such as cytokines, stress hormones, and cellular adhesion markers.

• Lengacher CA, Kip KE, Post-White J, Fitzgerald S, Newton C, Barta M, Jacobsen PB, Shelton MM, Moscoso M, Johnson-Mallard V, Harris E, Loftus L, Cox C, Le N, Goodman M, Djeu J, Widen RH, Bercu BB, Klein TW. Lymphocyte Recovery After Breast Cancer Treatment and Mindfulness-Based Stress Reduction (MBSR) Therapy. Biol Res Nurs. 2013 Jan;15(1):37-47. Pubmedid: 22084404.
• Kip KE, Sullivan KL, Lengacher CA, Rosenzweig L, Hernandez DF, Kadel R, Kozel FA, Shuman A, Girling SA, Hardwick MJ, Diamond DM. Brief treatment of co-occurring post-traumatic stress and depressive symptoms by use of accelerated resolution therapy(®). Front Psychiatry. 2013;4:11. Pubmedid: 23482431. Pmcid: PMC3591743.
• Lengacher CA, Shelton MM, Reich RR, Barta MK, Johnson-Mallard V, Moscoso MS, Paterson C, Ramesar S, Budhrani P, Carranza I, Lucas J, Jacobsen PB, Goodman MJ, Kip KE. Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). J Behav Med. 2012 Nov. Pubmedid: 23184061.
• Lengacher CA, Kip KE, Barta M, Post-White J, Jacobsen P, Groer M, Lehman B, Moscoso MS, Kadel R, Le N, Loftus L, Stevens CA, Malafa MP, Shelton MM. A pilot study evaluating the effect of mindfulness-based stress reduction on psychological status, physical status, salivary cortisol, and interleukin-6 among advanced-stage cancer patients and their caregivers. J Holist Nurs. 2012 Sep;30(3):170-185. Pubmedid: 22442202.
• Lengacher CA, Reich RR, Post-White J, Moscoso M, Shelton MM, Barta M, Le N, Budhrani P. Mindfulness based stress reduction in post-treatment breast cancer patients: an examination of symptoms and symptom clusters. J Behav Med. 2012 Feb;35(1):86-94. Pubmedid: 21506018.
• Lengacher CA, Johnson-Mallard V, Barta M, Fitzgerald S, Moscoso MS, Post-White J, Jacobsen PB, Molinari Shelton M, Le N, Budhrani P, Goodman M, Kip KE. Feasibility of a mindfulness-based stress reduction program for early-stage breast cancer survivors. J Holist Nurs. 2011 Jun;29(2):107-117. Pubmedid: 21041554.
• Lengacher CA, Johnson-Mallard V, Post-White J, Moscoso MS, Jacobsen PB, Klein TW, Widen RH, Fitzgerald SG, Shelton MM, Barta M, Goodman M, Cox CE, Kip KE. Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psychooncology. 2009 Dec;18(12):1261-1272. Pubmedid: 19235193.
• Beckstead J, Yang C, Lengacher C. Assessing cross-cultural validity of scales: A methodological review and illustrative example. Int J Nurs Stud. 2008 Jan;45(1):110-119. Pubmedid: 17081547.
• Yang C, Lengacher C, Beckstead J, Shiau S. The women's role strain inventory: A Chinese translation and psychometric analyses for Taiwanese women. Int J Nurs Stud. 2008 Jan;45(1):85-94. Pubmedid: 17010349.
• Lengacher C, Bennett M, Gonzalez L, Gilvary D, Cox C, Cantor A, Jacobsen PB, Yang C, Djeu J. Immune responses to guided imagery during breast cancer treatment. Biol Res Nurs. 2008 Jan;9(3):205-214. Pubmedid: 18077773.
• Gonzalez L, Lengacher C. Coping with breast cancer: a qualitative analysis of reflective journals. Issues Ment Health Nurs. 2007 May;28(5):489-510. Pubmedid: 17613149.
• Johnson-Mallard V, Lengacher C, Kromrey J, Campbell D, Jevitt C, Daley E, Schmitt K. Increasing Knowledge of Sexually Transmitted Infection Risk. Nurse Pract. 2007 Feb;32(2):26-32.
• Bennett M, Lengacher C. Humor and Laughter May Influence Health: II. Complementary Therapies and Humorin a Clinical Population. Evid Based Complement Alternat Med. 2006 Jun;3(2):187-90. Epub 2. Pubmedid: 16786047.
• Bennett MP, Lengacher CA. Humor and laughter may influence health. I. History and Background. Evid Based Complement Alternat Med. 2006 Mar;3(1):61-63. Pubmedid: 16550224.
• Lengacher C, Bennett M, Kip K, Gonzalez L, Jacobsen P, Cox C. Relief of symptoms, side effects, and psychological distress through use of complementary and alternative medicine in women with breast cancer. Oncol Nurs Forum. 2006 Jan;33(1):97-104. Pubmedid: 16470237.
• Wane D, Lengacher CA. Integrative review of lycopene and breast cancer. Oncol Nurs Forum. 2006 Jan;33(1):127-137. Pubmedid: 16470241.
• Lengacher C, Bennett M, Kipp K, Berarducci A, Cox C. Design and testing of the use of a complementary and alternative therapies survey in women with breast cancer. Oncol Nurs Forum. 2003;30(5):811-821. Pubmedid: 12949594.
• Lengacher C, Gonzalez L, Bennett M. The effects of relaxation-guided imagery on psychological variables and natural killer cell, and cytokine (IL-2) induced NK activity in breast cancer patients. Brain Behav Immun. 2002;16(2):198-198. Pubmedid: noPMID.
• Berarducci A, Lengacher C, Keller R. The impact of osteoporosis continuing education on nurses' knowledge and attitudes. J Contin Educ Nurs. 2002;33(5):210-216. Pubmedid: 12269759.
• Lengacher C, Bennett M, Kip K, Keller R, Smith L, LaVance M, Cox C, Reintgen D. Frequency of use of complementary alternative therapies in women with breast cancer. Oncol Nurs Forum. 2002;29(10):1445-1452. Pubmedid: 12432415.
• Lengacher C, Gonzalez L, Giuliano R, Reintgen D, Cox C. The process of clinical trials: a model for successful clinical trial participation. Oncol Nurs Forum. 2001;28(7):1115-1120. Pubmedid: 11517845.
• Moody L, Voss A, Lengacher C. Assessing abuse among the elderly living in public housing. J Nurs Meas. 2000;8(1):61-70. Pubmedid: 11026166.
• Berarducci A, Burns P, Lengacher C, Sellers E. Health-promoting educational practices related to osteoporosis. Appl Nurs Res. 2000;13(4):173-180. Pubmedid: 11078782.
• Page P, Lengacher C, Holsonback C, Himmegreen D, Pappalardo L, Lipano M, Lein K. Quality of care-risk adjustment outcomes research model: testing the effects of a community based educational self management program for children with asthma. Nurs Connect. 1999;12(3):47-58. Pubmedid: 10788904.
• Gonzalez L, Web M, Lowry L, Lengacher C. Baccalaureate nursing education and home health: a collaborative alliance. Nurs Connect. 1999;12(1):35-48. Pubmedid: 10401400.
• Bennett M, Lengacher C. Use of complementary therapies in a rural cancer population. Oncol Nurs Forum. 1999;26(8):1287-1294. Pubmedid: 10497768.
• Mabe PR, Lengacher CA. Redesigning emergency care: financial and cost analysis of services provided. Nurs Econ. 1998 Mar;16(2):75-82. Pubmedid: 9592522 .
• Bennett M, Lengacher C. Design and testing of a complementary therapy rating scale in rural persons with cancer. Alternative Health Pract. 1998;4(3):179-202. Pubmedid: noPMID.
• Lengacher C, Bennett M, Gonzalez L, Cox C, Reintgen D, Cantor A, Djeu J. Psychoneuroimmunology, immune system link, stress, depression,health behaviors and breast cancer. Alternative Health Care. 1998;4(2):95-108. Pubmedid: noPMID.
• Berarducci A, Lengacher C. Self-efficacy: an essential component of advanced practice nursing. Nurs Connect. 1998;2(1):55-67. Pubmedid: noPMID.
• Lengacher C, Bennett M, Gonzalez L, Cox C, Reintgen D, Cantor A, Djeu J. Review of literature: Psychoneuroimmunology, immune system link: stress, depression, health behaviors and breast cancer. Alternative Health Pract. 1998;4:95-107. Pubmedid: noPMID.
• Mabe, P, Lengacher C. Redesigning emergency care: financial and cost analysis of services provided. Nurs Econ. 1998;16(2):75-82. Pubmedid: 9592522.
• Lengacher CA. A reliability and validity study of the Women's Role Strain Inventory. J Nurs Meas. 1997 Dec;5(2):139-150. Pubmedid: 9538586 .
• Lengacher CA, Mabe PR, Heinemann D, VanCott ML, Kent K, Swymer S. Collaboration in research: testing the PIPC model on clinical and nonclinical outcomes. Nursingconnections. 1997 Apr;10(1):17-30. Pubmedid: 9171689 .
• VanCott ML, Lengacher CA, Heinemann D, Mabe P, Swymer S, Bistritz D. The use of focus groups to assist in the design and implementation of a new nursing practice model. J Nurs Staff Dev. 1997 Mar;13(2):83-87. Pubmedid: 9155343 .
• Lengacher C. A reliability and validity study of the Women's Role Strain Inventory. J Nurs Measure. 1997;5(2):139-150. Pubmedid: 9538586.
• VanCott M, Lengacher C, Heinemann D, Mabe P, Swymer S, Bistritz D. 1997;33-37.
• VanCott M, Lengacher C, Heinemann D, Mabe P, Swymer S, Bistritz D. The use of focus groups to assist in designing a new nursing practice model. J Nurs Staff Dev. 1997;13(2):83-87. Pubmedid: 9155343.
• Lengacher C. Collaboration in research: testing the PIPC model on clinical and nonclinical outcomes. Nurs Connect. 1997;10(1):117-130. Pubmedid: 9171689.
• Heinemann D, Lengacher CA, VanCott ML, Mabe P, Swymer S. Partners in patient care: measuring the effects on patient satisfaction and other quality indicators. Nurs Econ. 1996 Sep;14(5):276-285. Pubmedid: 8998022 .
• Lengacher CA, Mabe PR, Heinemann D, VanCott ML, Swymer S, Kent K. Effects of the PIPC model on outcome measures of productivity and costs. Nurs Econ. 1996 Jul;14(4):205-12, 238. Pubmedid: 8826307 .
• Lengacher C, Mabe C, Heinemann D, VanCott M, Swymer S, Kent K. Effects of the partner's in care practice model on outcome measures of productivity and costs. Nurs Econ. 1996;14(4):205-212+. Pubmedid: 8826307.
• Heinemann D, Lengacher C, VanCott M, Mabe P, Swymer S. Partners in care: measuring the effects on patient satisfaction and selected quality of care indicators. Nurs Econ. 1996;14(5):276-285. Pubmedid: 8998022.
• Lengacher CA, Mabe PR, Kent K, Allred R. Design, implementation, and evaluation of an educational program for a new practice model. J Nurs Staff Dev. 1995 Jul;11(4):195-200. Pubmedid: 7643228 .
• Lengacher CA, Mabe PR, VanCott ML, Heinemann D, Kent K. Team-building process in launching a practice model. Nursingconnections. 1995 Jun;8(2):51-59. Pubmedid: 7651550 .
• Lengacher C, Mabe P, VanCott M, Heinemann D, Kent K. Team-building process in launching a practice model. Nurs Connect. 1995;8(2):51-59. Pubmedid: 7651550.
• Lengacher C, Mabe P, Kent K, Allred R. Design, implementation and evaluation of an educational program for a new nursing practice model. J Nurs Staff Dev. 1995;11(4):195-220. Pubmedid: 7643228.
• Lengacher CA, Kent K, Mabe PR, Heinemann D, VanCott ML, Bowling CD. Effects of the partners in care practice model on nursing outcomes. Nurs Econ. 1994 Nov;12(6):300-308. Pubmedid: 7885486 .
• Lengacher CA. Effects of professional development seminars on role conception, role deprivation, and self-esteem of generic baccalaureate students. Nursingconnections. 1994 Apr;7(1):21-34. Pubmedid: 8202168 .
• Lengacher C, Kent K, Mabe P, Heinemann D, VanCott M, Bowling C. Effects of the partners in care practice model on nursing outcomes. Nurs Econ. 1994;12(6):300-308.
• Lengacher CA, Mabe PR, Bowling CD, Heinemann D, Kent K, Van Cott ML. Redesigning nursing practice. The partners in patient care model. J Nurs Adm. 1993 Dec;23(12):31-37. Pubmedid: 8254434 .
• Lengacher CA. Comparative analysis of role strain and self-esteem across academic programs. Nursingconnections. 1993 Oct;6(3):33-46. Pubmedid: 8107896 .
• Lengacher CA. Development of a predictive model for role strain in registered nurses returning to school. J Nurs Educ. 1993 Sep;32(7):301-308. Pubmedid: 828446073.
• VanCott ML, Lengacher C. Review of research related to educational re-entry for the registered nurse: 1985-1991. Nln Publ. 1993 Apr;(14-2511):79-96. Pubmedid: 8516115 .
• Lengacher CA, Mabe PR. Nurse extenders. J Nurs Adm. 1993 Mar;23(3):16-19. Pubmedid: 8473922 .
• Lengacher CA. Development and study of an instrument to measure role strain. J Nurs Educ. 1993 Feb;32(2):71-77. Pubmedid: 8388049 .
• Lengacher C, Mabe P, Bowling C, Heinemann D, Kent K, VanCott M. Redesigning nursing practice: the partners in patient care model. J Nurs Adm. 1993;23(12):31-37.
• Lengacher CA, Tittle MB. Critical care in a baccalaureate program. Nursingconnections. 1992 Apr;5(1):3-10. Pubmedid: 1589042 .
• Lengacher CA, Keller R. Comparison of role conception and role deprivation in LPN-transition students and traditional ADN students in a specially designed associate program. J Nurs Educ. 1992 Feb;31(2):79-84. Pubmedid: 1314301 .
• Lengacher CA, Gorzeman J. Partnership between education and service for psychiatric staff education. J Nurs Staff Dev. 1992 Jan;8(1):14-17. Pubmedid: 1740724 .
• Lengacher CA. The economic benefits to service and education of a critical care learning experience for baccalaureate students. Nurs Econ. 1992 Jan;10(1):72-73. Pubmedid: 1732823 .
• Lengacher CA. An articulation model encompassing structure and process. Adv Clin Care. 1990 Sep;5(5):42-44. Pubmedid: 2393508 .
• Lengacher CA, Keller R. Academic predictors of success on the NCLEX-RN examination for associate degree nursing students. J Nurs Educ. 1990 Apr;29(4):163-169. Pubmedid: 2159063 .
• Curran CL, Lengacher CA. RN re-entry programs: programmatic and personal considerations. Nurse Educ. 1982 May;7(3):29-32. Pubmedid: 6918830 .
• Lengacher C. Role strain, role stress, and anxiety in nursing education: theoretical and research analysis from 1988-1995. In: Stevens K, ed. Review of research in nursing education: volume VI. New York, NY: National Leauge For Nursing Press; 1996;40-66.
• Berarducci A, Lengacher CA. Self-efficacy: an essential component of advanced-practice nursing. Nursingconnections. 1998 Spr;11(1):55-67. Pubmedid: 9644482 .
• Lengacher C. Psychoneuroimmunology. In: Clark C, ed. The encyclopedia of complementary health practices. New York, NY: Springer Publishers; 1999;459-461.
• Lengacher, Sellers E, Strickland O, Dilorio C. Study of the realiability/validity of the women's role strain inventory. In: Measurement of Nursing Outcomes: Focus on the patient/client outcomes. 2nd ed. New York, NY: Springer Publishers; 2003;109-127.