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Amod Sarnaik, MD

Where You Are:
Amod Sarnaik, MD

Assistant Member

Office  (813) 745-8582

Education And Training
  • Fellow, University of South Florida, 2009 - Surgical Oncology Fellow, Moffitt Cancer Center
  • Resident & Chief Resident, University of Cincinnati, 2006 - Surgery
  • Fellow, University of Cincinnati, 2003 - Howard Hughes Investigational Postdoctoral Fellow, Molecular Genetics
  • Resident, University of Cincinnati, 2001 - Surgery
  • Intern, University of Cincinnati, 2000 - Surgery
  • MD, University of Michigan, 1999
  • BA, Harvard University, 1995 - Biology


Dr. Sarnaik's primary research interest involves investigation of novel immunotherapeutics in the treatment of melanoma.  This includes tumor-based vaccines, immune-activating antibodies, targeted inhibition of oncogenic proteins, and autologous T cell therapy.

  • Deneve JL, Turaga KK, Marzban SS, Puleo CA, Sarnaik AA, Gonzalez RJ, Sondak VK, Zager JS. Single-institution Outcome Experience Using AlloDerm® as Temporary Coverage or Definitive Reconstruction for Cutaneous and Soft Tissue Malignancy Defects. Am Surg. 2013 May;79(5):476-482. Pubmedid: 23635582.
  • Ghansah T, Vohra N, Kinney K, Weber A, Kodumudi K, Springett G, Sarnaik AA, Pilon-Thomas S. Dendritic cell immunotherapy combined with gemcitabine chemotherapy enhances survival in a murine model of pancreatic carcinoma. Cancer Immunol Immunother. 2013 Apr. Pubmedid: 23604104.
  • Youn JI, Kumar V, Collazo M, Nefedova Y, Condamine T, Cheng P, Villagra A, Antonia S, McCaffrey JC, Fishman M, Sarnaik A, Horna P, Sotomayor E, Gabrilovich DI. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nat Immunol. 2013 Mar;14(3):211-220. Pubmedid: 23354483. Pmcid: PMC3578019.
  • Toomey PG, Vohra NA, Ghansah T, Sarnaik AA, Pilon-Thomas SA. Immunotherapy for gastrointestinal malignancies. Cancer Control. 2013 Jan;20(1):32-42. Pubmedid: 23302905.
  • Chacon JA, Wu RC, Sukhumalchandra P, Molldrem JJ, Sarnaik A, Pilon-Thomas S, Weber J, Hwu P, Radvanyi L. Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8(+) Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy. PLoS One. 2013;8(4):e60031. Pubmedid: 23560068.
  • Kodumudi KN, Weber A, Sarnaik AA, Pilon-Thomas S. Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma. J Immunol. 2012 Dec;189(11):5147-5154. Pubmedid: 23100512. Pmcid: PMC3505990.
  • Han D, Zager JS, Han G, Marzban SS, Puleo CA, Sarnaik AA, Reed D, Messina JL, Sondak VK. The unique clinical characteristics of melanoma diagnosed in children. Ann Surg Oncol. 2012 Nov;19(12):3888-3895. Pubmedid: 22864798.
  • Han D, Yu D, Zhao X, Marzban SS, Messina JL, Gonzalez RJ, Wayne Cruse C, Sarnaik AA, Puleo C, Sondak VK, Zager JS. Sentinel Node Biopsy is Indicated for Thin Melanomas ≥0.76 mm. Ann Surg Oncol. 2012 Oct;19(11):3335-3342. Pubmedid: 22766986.
  • Pilon-Thomas S, Kuhn L, Ellwanger S, Janssen W, Royster E, Marzban S, Kudchadkar R, Zager J, Gibney G, Sondak VK, Weber J, Mulé JJ, Sarnaik AA. Efficacy of Adoptive Cell Transfer of Tumor-infiltrating Lymphocytes After Lymphopenia Induction for Metastatic Melanoma. J Immunother. 2012 Oct;35(8):615-620. Pubmedid: 22996367.
  • Paraiso KH, Haarberg HE, Wood E, Rebecca VW, Chen YA, Xiang Y, Ribas A, Lo RS, Weber JS, Sondak VK, John JK, Sarnaik AA, Koomen JM, Smalley KS. The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms. Clin Cancer Res. 2012 Aug;18(9):2502-2514. Pubmedid: 22351686. Pmcid: PMC3398738.
  • Wang W, Yu D, Sarnaik AA, Yu B, Hall M, Morelli D, Zhang Y, Zhao X, Weber JS. Biomarkers on melanoma patient T Cells associated with ipilimumab treatment. J Transl Med. 2012 Jul;10(1):146. Pubmedid: 22788688.
  • Sondak VK, Sarnaik AA. Minimizing Morbidity while Preserving Outcome after Inguinal Lymphadenectomy: Navigating between Scylla and Charybdis. Ann Surg Oncol. 2011 Apr;18(4):909-911. Pubmedid: 21246401.
  • Sarnaik AA, Yu B, Yu D, Morelli D, Hall M, Bogle D, Yan L, Targan S, Solomon J, Nichol G, Yellin M, Weber JS. Extended dose ipilimumab with a peptide vaccine: immune correlates associated with clinical benefit in patients with resected high-risk stage IIIc/IV melanoma. Clin Cancer Res. 2011 Feb;17(4):896-906. Pubmedid: 21106722. Pmcid: PMC3041838.
  • Sarnaik AA, Meade T, King J, Acs G, Hoover S, Cox CE, Carter WB, Laronga C. Adenoid cystic carcinoma of the breast: a review of a single institution's experience. Breast J. 2010 Mar-Apr;16(2):208-210. Pubmedid: 20030648.
  • Sarnaik AA, Lien MH, Nghiem P, Bichakjian CK. Clinical recognition, diagnosis, and staging of merkel cell carcinoma, and the role of the multidisciplinary management team. Curr Probl Cancer. 2010 Jan;34(1):38-46. Pubmedid: 20371073.
  • Sarnaik AA, Zager JS, Cox LE, Ochoa TM, Messina JL, Sondak VK. Routine Omission of Sentinel Lymph Node Biopsy for Merkel Cell Carcinoma <= 1 cm Is Not Justified. J Clin Oncol. 2010 Jan;28(1):e7-e7. Pubmedid: 19933899.
  • Sarnaik AA, Puleo CA, Zager JS, Sondak VK. Limiting the morbidity of inguinal lymphadenectomy for metastatic melanoma. Cancer Control. 2009 Jul;16(3):240-247. Pubmedid: 19556964.
  • Sarnaik AA, Weber JS. Recent advances using anti-CTLA-4 for the treatment of melanoma. Cancer J. 2009 May;15(3):169-173. Pubmedid: 19556898.
  • Qian J, Sarnaik AA, Bonney TM, Keirsey J, Combs KA, Steigerwald K, Acharya S, Behbehani GK, Barton MC, Lowy AM, Groden J. The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl terminus. Gastroenterology. 2008 Jul;135(1):152-162. Pubmedid: 18474248. Pmcid: PMC2832605.
  • Sarnaik AA, Zager JS, Sondak VK. Multidisciplinary management of special melanoma situations: oligometastatic disease and bulky nodal sites. Curr Oncol Rep. 2007 Sep;9(5):417-427. Pubmedid: 17706171.
  • Sarnaik AA, Sussman JJ, Ahmad SA, Lowy AM. Technology of intraperitoneal chemotherapy administration: a survey of techniques with a review of morbidity and mortality. Surg Oncol Clin N Am. 2003 Jul;12(3):849-863. Pubmedid: 14567036.
  • Sarnaik AA, Saad AG, Mutema GK, Martin SP, Attar A, Lowy AM. Osteoclast-like giant cell tumor of the pancreas associated with a mucinous cystadenocarcinoma. Surgery. 2003 Jun;133(6):700-701. Pubmedid: 12796742.

Office: (813) 745-8582

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